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Gastroenterology 159 , 21632180.e6 (2020)

Our study addresses this by using an inducible system, which allows us to exclusively observe the extent of the p53-specific effect and suggests that even the prototypical conformational mutant R175H has a modest effect on response to APR-246

A colorimetric kinetic assay for glutathione peroxidase activity that measures NADPH consumption at 340 nm